• Expression of miR-24-1-5p in Tumor Tissue Influences Prostate Cancer Recurrence: The PROCA-life Study 

      Stikbakke, Einar; Wilsgaard, Tom; Haugnes, Hege Sagstuen; Pedersen, Mona Irene; Knutsen, Tore; Støyten, Martin; Giovannucci, Edward; Eggen, Anne Elise; Thune, Inger; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-23)
      The role of miR-24-1-5p and its prognostic implications associated with prostate cancer are mainly unknown. In a population-based cohort, the Prostate Cancer Study throughout life (PROCA-life), all men had a general health examination at study entry and were followed between 1994 and 2016. Patients with available tissue samples after a prostatectomy with curative intent were identified (n = 189). ...
    • Improvement in early continence after introduction of periurethral suspension stitch in robotic prostatectomy 

      Aarsæther, Erling Johan; Roaldsen, Marius; Knutsen, Tore; Patel, Hiten R.; Soltun, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-14)
      Early urinary incontinence remains a major source of morbidity for patients undergoing robotic prostatectomy. The purpose of the study was to determine whether the introduction of a suspension stitch would improve early urinary continence rates in patients undergoing robotic prostatectomy for localized prostate cancer at our department. We retrospectively reviewed patients undergoing robotic ...
    • Inflammatory serum markers and risk and severity of prostate cancer: The PROCA‐life study 

      Stikbakke, Einar; Richardsen, Elin; Knutsen, Tore; Wilsgaard, Tom; Giovannucci, Edward L; McTiernan, Anne; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
      Whether chronic inflammation mirrored by high levels of systemic inflammatory markers such as high sensitive‐CRP (hs‐CRP) and white blood cell count (WBC) are associated with prostate cancer development remains unclear. In the Prostate Cancer Study throughout Life (PROCA‐<i>life</i>), a prospective population‐based cohort study, 7,356 men were included. Prediagnostic WBC and hs‐CRP were assessed ...
    • The Longitudinal Course of Prospectively Recorded Patient-reported Outcomes in Prostate Cancer Patients Treated with Surgery and Salvage Radiotherapy 

      Hjelle, Line Veronika; Sælen, Marie; Aarsæther, Erling Johan; Knutsen, Tore; Andersen, Sigve; Bentzen, Anne Gry; Richardsen, Elin; Wilsgaard, Tom; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-13)
      Background - Patient-reported outcome measures (PROMs) after prostate cancer (PC) treatment, including both radical prostatectomy (RP) and salvage radiation therapy (SRT), are under-reported.<p> <p>Objective - To investigate PROMs longitudinally from before SRT until 18 mo after SRT for men treated with contemporary treatment modalities.<p> <p>Design, setting, and participants - This prospective, ...
    • Patient-reported outcomes after curative treatment for prostate cancer with prostatectomy, primary radiotherapy or salvage radiotherapy 

      Sælen, Marie Grøn; Hjelle, Line Veronika; Aarsæther, Erling Johan; Knutsen, Tore; Andersen, Sigve; Bentzen, Anne Gry; Richardsen, Elin; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-24)
      Trials reporting adverse health outcomes (AHOs) in terms of patient-reported outcome measures (PROMs) after contemporary curative treatment of prostate cancer (PC) are hampered by study heterogeneity and lack of new treatment techniques. Particularly, the evidence regarding toxicities after radiotherapy (RT) with the volumetric arc therapy (VMAT) technique is limited, and comparisons between men ...
    • Statusbericht aus Norwegen: Implementierung von Patientenbeteiligung im norwegischen Gesundheitswesen 

      Kasper, Jürgen; Lager, Anne Regine; Rumpsfeld, Markus; Kienlin, Simone Maria; Smestad, Kristine Hoel; Bråthen, Tone; Ankell, Holly; Knutsen, Tore; Kløvtveit, Rune; Gulbrandsen, Pål; Vandvik, Per Olav; Heen, Anja Fog; Flottorp, Signe; Tollåli, Geir; Eiring, Øystein (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-22)
      Norway has traditionally high standards regarding civil rights particularly emphasizing equal access to societal resources including health care. This background and the health care system’s centralized national organization make it perfectly suited for implementation of shared decision making (SDM). In recent years, great efforts have been made by policy- makers, regional health authorities and ...
    • Systolic and diastolic blood pressure, prostate cancer risk, treatment, and survival. The PROCA-life study 

      Stikbakke, Einar; Schirmer, Henrik; Knutsen, Tore; Støyten, Martin; Wilsgaard, Tom; Giovannucci, Edward L.; McTiernan, Anne; Eggen, Anne Elise; Haugnes, Hege Sagstuen; Richardsen, Elin; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-22)
      Background: Inflammation has been linked to prostate cancer and hypertension, but it remains equivocal whether elevated blood pressure (BP) influence prostate cancer risk and survival.<p> <p>Method: Using Cox regression models, we examined the association between prediagnostic BP and prostate cancer risk among 12,271 men participating in the Prostate Cancer throughout life (PROCA-life) study. ...